Conditional Likelihood Methods for Haplotype-Based Association Analysis Using Matched Case-Control Data
نویسندگان
چکیده
منابع مشابه
Conditional likelihood methods for haplotype-based association analysis using matched case-control data.
Genetic epidemiologists routinely assess disease susceptibility in relation to haplotypes, that is, combinations of alleles on a single chromosome. We study statistical methods for inferring haplotype-related disease risk using single nucleotide polymorphism (SNP) genotype data from matched case-control studies, where controls are individually matched to cases on some selected factors. Assuming...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2007
ISSN: 0006-341X
DOI: 10.1111/j.1541-0420.2007.00797.x